Holden Karnofsky
Co-founder of GiveWell and Open Philanthropy; has worked at Anthropic since 2025
Co-founder of GiveWell and Open Philanthropy; has worked at Anthropic since 2025
Every podcast episode featuring Holden Karnofsky that Attunex has found: 24 interviews and appearances across 15 shows between 2011 and 2026. Most often on 80,000 Hours Podcast (10). Often in conversation with Rob Wiblin. Follow Holden in Attunex to get new appearances automatically, each with an on-device transcript and summary.
Follow Holden Karnofsky in AttunexUpdated 2026-10-14.
Here's Holden Karnofsky: I tend to think it's worse than 51/49. I tend to think we’re always going to be prone to overestimate how robustly good our actions are. And the more we learn about all the…
For years, AI safety work mostly meant theorising about the ‘alignment problem’ or trying to convince people to give a damn. If you could find a way to help, the work was frustrating and…
Anthropic has revised its Responsible Scaling Policy to v3. The changes involved include abandoning many previous commitments, including one not to move ahead if doing so would be dangerous, citing…
All views are my own, not Anthropic's. This post assumes Anthropic's announcement of RSP v3.0 as background. Today, Anthropic released its Responsible Scaling Policy 3.0. The official announcement…
For years, working on AI safety usually meant theorising about the ‘alignment problem’ or trying to convince other people to give a damn. If you could find any way to help, the work was frustrating…
This is a transcript of a conversation between Paul Christiano and Eliezer Yudkowsky, with comments by Rohin Shah, Beth Barnes, Richard Ngo, and Holden Karnofsky, continuing the Late 2021 MIRI…
This post is a transcript of a multi-day discussion between Paul Christiano, Richard Ngo, Eliezer Yudkowsky, Rob Bensinger, Holden Karnofsky, Rohin Shah, Carl Shulman, Nate Soares, and Jaan Tallinn,…
Read the full transcript here. Has society reached ‘peak progress’? Can we sustain the level of economic growth that technology has enabled over the last century? Have researchers plucked the last of…
Become a founder of an organisation tackling one of the world’s most pressing problems. Narrated by AI. --- Outline: (01:32) Recommended (01:41) Review status (01:47) Why might founding a new project…
What if there’s something it’s like to be a shrimp — or a chatbot? For centuries, humans have debated the nature of consciousness, often placing ourselves at the very top. But what about the minds of…
How do you navigate a career path when the future of work is uncertain? How important is mentorship versus immediate impact? Is it better to focus on your strengths or on the world’s most pressing…
This is a Forum Team crosspost from Substack. Matt would like to add: "Epistemic status = incomplete speculation; posted here at the Forum team's request" When you ask prominent Effective Altruists…
In a recent Wired article about Anthropic, there's a section where Anthropic's president, Daniela Amodei, and early employee Amanda Askell seem to suggest there's little connection between Anthropic…
"There’s almost no story of the future going well that doesn’t have a part that’s like '…and no evil person steals the AI weights and goes and does evil stuff.' So it has highlighted the importance…
Will LLMs soon be made into autonomous agents? Will they lead to job losses? Is AI misinformation overblown? Will it prove easy or hard to create AGI? And how likely is it that it will feel like…
Audio versions of blogs and papers from BlueDot courses. This article from Holden Karnofsky, now a visiting scholar at the Carnegie Endowment for International Peace, discusses "If-Then" commitments…
With kids very much on the team's mind we thought it would be fun to review some comments about parenting featured on the show over the years, then have hosts Luisa Rodriguez and Rob Wiblin react to…
Durante el presente, siglo nuestra civilización podría desarrollar tecnologías que permitan una rápida expansión por la galaxia, actualmente vacía. Por lo tanto, este siglo podría determinar todo el…
Este artículo ofrece un resumen de las múltiples perspectivas consideradas anteriormente en la serie sobre la cuestión de cuándo deberíamos esperar que se desarrolle una IA transformadora. A…
Audio versions of blogs and papers from BlueDot courses. This blog post from Holden Karnofsky, Open Philanthropy’s Director of AI Strategy, explains how advanced AI might overpower humanity. It…
Esta es la última entrada de la serie “el siglo más importante”. Cuando se trata de llamar la atención sobre un problema poco valorado, lo normal es terminar con un “llamamiento a la acción”: una…
Estamos acostumbrados a que la economía global crezca un par de puntos porcentuales al año, pero en realidad se trata de una situación muy inusual. Con el tiempo, el crecimiento se ha acelerado:…
This is a selection of highlights from episode #158 of The 80,000 Hours Podcast. These aren't necessarily the most important, or even most entertaining parts of the interview — and if you enjoy this,…
Back in 2007, Holden Karnofsky cofounded GiveWell, where he sought out the charities that most cost-effectively helped save lives. He then cofounded Open Philanthropy, where he oversaw a team making…
Wie weit lassen sich derzeitige Trends wie das derzeitige Wirtschaftswachstum extrapolieren? Auf einem geschichtlichen Maßstab: nicht sehr lang, meint Holden Karnofsky. Wie wird es also mit uns…
Befinden wir uns an einem menschheitsgeschichtlich wichtigen Zeitpunkt? Holden Karnofsky, der Autor dieses Textes, meint: Einiges spricht dafür. Der vollständige Text mit allen Diagrammen ist zu…
Könnte es sich bei diesem Jahrhundert um einen geschichtlichen Dreh- und Angelpunkt handelt? Für diese Hypothese argumentiert Holden Karnofksy in seiner Beitragsreihe Das wichtigste Jahrhundert .…
Success without dignity: a nearcasting story of avoiding catastrophe by luck, by Holden Karnofsky.…
Podcast : The Gray Area with Sean Illing Episode : Can effective altruism be redeemed? Release date : 2023-01-23 Get Podcast Transcript → powered by Listen411 - fast audio-to-text and summarization…
Guest host Sigal Samuel talks with Holden Karnofsky about effective altruism, a movement flung into public scrutiny with the collapse of Sam Bankman-Fried and his crypto exchange, FTX. They discuss…
Holden Karnofsky is the co-CEO of Open Philanthropy and co-founder of GiveWell. He is also the author of one of the most interesting blogs on the internet, Cold Takes. We discuss: * Are we living in…
This episode continues the fascinating-slash-frightening journey I’ve been on with you, to understand what we should prioritise as we face potential existential end times. Today’s guest, Harvard…
The future can look like a scary place. Climate change is upon us and we’re in the throes of huge technological change without a clear idea of where we will land. Added to which, we are constantly…
The Sunday Times’ tech correspondent Danny Fortson brings on Holden Karnofsky, founder of GiveWell, to talk about philanthropy (3:30), teaming up with Facebook co-founder Dustin Moskowitz and…
Do we actually know how much good our charitable donations do? This is the question that jump-started Holden Karnofsky’s current career. He was working at a hedge fund and wanted to figure out how to…
This is the full series of Cold Takes posts listed here: https://www.cold-takes.com/roadmap-for-the-most-important-century-series/
Holden Karnofsky helped create two of the most influential organisations in the effective philanthropy world. So when he outlines a different perspective on career advice than the one we present at…
Will the future of humanity be wild, or boring? It's natural to think that if we're trying to be sober and measured, and predict what will really happen rather than spin an exciting story, it's more…
The Green Revolution averted mass famine during the 20th century. The contraceptive pill gave women unprecedented freedom in planning their own lives. Both are widely recognised as scientific…
Our guest Holden Karnofsky joins us to discuss Givewell, the nonprofit organization he founded. Givewell is devoted to investigating charities and NGOs to determine how much of an impact they’re…
The Green Revolution averted mass famine during the 20th century. The contraceptive pill gave women unprecedented freedom in planning their own lives. Both are widely recognised as scientific…
Our guest Holden Karnofsky joins us to discuss Givewell, the nonprofit organization he founded. Givewell is devoted to investigating charities and NGOs to determine how much of an impact they're…